abstract：:The YidC/OxaI/Alb3 family of membrane proteins is involved in the biogenesis of integral membrane proteins in bacteria, mitochondria, and chloroplasts. Gram-positive bacteria often contain multiple YidC paralogs that can be subdivided into two major classes, namely, YidC1 and YidC2. The Streptococcus mutans YidC1 and ...

journal_title：Journal of bacteriology

authors： Wu ZC,de Keyzer J,Berrelkamp-Lahpor GA,Driessen AJ

更新日期：2013-10-01 00:00:00

abstract：:The foliar pathogen Pseudomonas syringae is a useful model for understanding the role of stress adaptation in leaf colonization. We investigated the mechanistic basis of differences in the osmotolerance of two P. syringae strains, B728a and DC3000. Consistent with its higher survival rates following inoculation onto l...

journal_title：Journal of bacteriology

authors： Freeman BC,Chen C,Yu X,Nielsen L,Peterson K,Beattie GA

更新日期：2013-10-01 00:00:00

abstract：:Motility of bacteria like Salmonella enterica is a highly regulated process that responds to a variety of internal and external stimuli. A hierarchy of three promoter classes characterizes the Salmonella flagellar system, and the onset of flagellar gene expression depends on the oligomeric regulatory complex and class...

journal_title：Journal of bacteriology

authors： Singer HM,Erhardt M,Hughes KT

更新日期：2013-09-01 00:00:00

abstract：:Pyridine-2,6-bis(thiocarboxylate) (PDTC), produced by certain pseudomonads, is a sulfur-containing siderophore that binds iron, as well as a wide range of transition metals, and it affects the net hydrolysis of the environmental contaminant carbon tetrachloride. The pathway of PDTC biosynthesis has not been defined. H...

journal_title：Journal of bacteriology

authors： Lewis TA,Glassing A,Harper J,Franklin MJ

更新日期：2013-09-01 00:00:00

abstract：:Coxiella burnetii, the etiological agent of acute and chronic Q fever in humans, is a naturally intracellular pathogen that directs the formation of an acidic Coxiella-containing vacuole (CCV) derived from the host lysosomal network. Central to its pathogenesis is a specialized type IVB secretion system (T4SS) that de...

journal_title：Journal of bacteriology

authors： Weber MM,Chen C,Rowin K,Mertens K,Galvan G,Zhi H,Dealing CM,Roman VA,Banga S,Tan Y,Luo ZQ,Samuel JE

更新日期：2013-09-01 00:00:00

abstract：:Nε-lysine acetylation was recently discovered on many bacterial proteins that function in diverse cellular processes. Thus, many questions remain unanswered. For example, what mechanisms regulate lysine acetylation? Does acetylation affect physiology? To help answer these questions, we studied the Escherichia coli res...

journal_title：Journal of bacteriology

authors： Hu LI,Chi BK,Kuhn ML,Filippova EV,Walker-Peddakotla AJ,Bäsell K,Becher D,Anderson WF,Antelmann H,Wolfe AJ

更新日期：2013-09-01 00:00:00

abstract：:The riboflavin analog roseoflavin is an antibiotic produced by Streptomyces davawensis. Riboflavin transporters are responsible for roseoflavin uptake by target cells. Roseoflavin is converted to the flavin mononucleotide (FMN) analog roseoflavin mononucleotide (RoFMN) by flavokinase and to the flavin adenine dinucleo...

journal_title：Journal of bacteriology

authors： Langer S,Hashimoto M,Hobl B,Mathes T,Mack M

更新日期：2013-09-01 00:00:00

abstract：:Energy-coupling factor (ECF) transporters form a large group of vitamin uptake systems in prokaryotes. They are composed of highly diverse, substrate-specific, transmembrane proteins (S units), a ubiquitous transmembrane protein (T unit), and homo- or hetero-oligomeric ABC ATPases. Biotin transporters represent a spec...

journal_title：Journal of bacteriology

authors： Finkenwirth F,Kirsch F,Eitinger T

更新日期：2013-09-01 00:00:00

abstract：:Obligate intracellular bacteria comprising the order Chlamydiales lack the ability to synthesize nucleotides de novo and must acquire these essential compounds from the cytosol of the host cell. The environmental protozoan endosymbiont Protochlamydia amoebophila UWE25 encodes five nucleotide transporters with specific...

journal_title：Journal of bacteriology

authors： Fisher DJ,Fernández RE,Maurelli AT

更新日期：2013-08-01 00:00:00

abstract：:The genome of the Philadelphia-1 strain of Legionella pneumophila, the causative organism of Legionnaires' disease, encodes two virulence-associated type 4 secretion systems (T4SSs), the Dot/Icm type 4B (T4BSS) and the Lvh type 4A (T4ASS). Broth stationary-phase cultures of most dot/icm mutants are defective in entry ...

journal_title：Journal of bacteriology

authors： Bandyopadhyay P,Lang EA,Rasaputra KS,Steinman HM

更新日期：2013-08-01 00:00:00

abstract：:Germination of dormant Bacillus subtilis spores with specific nutrient germinants is dependent on a number of inner membrane (IM) proteins, including (i) the GerA, GerB, and GerK germinant receptors (GRs) that respond to nutrient germinants; (ii) the GerD protein, essential for optimal GR function; and (iii) SpoVA pro...

journal_title：Journal of bacteriology

authors： Stewart KA,Setlow P

更新日期：2013-08-01 00:00:00

abstract：:Cytochrome bd oxidase operons from more than 50 species of bacteria contain a short gene encoding a small protein that ranges from ∼30 to 50 amino acids and is predicted to localize to the cell membrane. Although cytochrome bd oxidases have been studied for more than 70 years, little is known about the role of this sm...

journal_title：Journal of bacteriology

authors： VanOrsdel CE,Bhatt S,Allen RJ,Brenner EP,Hobson JJ,Jamil A,Haynes BM,Genson AM,Hemm MR

更新日期：2013-08-01 00:00:00

abstract：:The butyrogenic genes from Clostridium difficile DSM 1296(T) have been cloned and expressed in Escherichia coli. The enzymes acetyl-coenzyme A (CoA) C-acetyltransferase, 3-hydroxybutyryl-CoA dehydrogenase, crotonase, phosphate butyryltransferase, and butyrate kinase and the butyryl-CoA dehydrogenase complex composed o...

journal_title：Journal of bacteriology

authors： Aboulnaga el-H,Pinkenburg O,Schiffels J,El-Refai A,Buckel W,Selmer T

更新日期：2013-08-01 00:00:00

abstract：:Pseudomonas aeruginosa hemolytic phospholipase C (PlcH) degrades phosphatidylcholine (PC), an abundant lipid in cell membranes and lung surfactant. A ΔplcHR mutant, known to be defective in virulence in animal models, was less able to colonize epithelial cell monolayers and was defective in biofilm formation on plasti...

journal_title：Journal of bacteriology

authors： Jackson AA,Gross MJ,Daniels EF,Hampton TH,Hammond JH,Vallet-Gely I,Dove SL,Stanton BA,Hogan DA

更新日期：2013-07-01 00:00:00

abstract：:Flavobacterium johnsoniae cells move rapidly over surfaces by gliding motility. Gliding results from the movement of adhesins such as SprB and RemA along the cell surface. These adhesins are delivered to the cell surface by a Bacteroidetes-specific secretion system referred to as the type IX secretion system (T9SS). G...

journal_title：Journal of bacteriology

authors： Shrivastava A,Johnston JJ,van Baaren JM,McBride MJ

更新日期：2013-07-01 00:00:00

abstract：:During the transition from a free-swimming, single-cell lifestyle to a sessile, multicellular state called a biofilm, bacteria produce and secrete an extracellular matrix comprised of nucleic acids, exopolysaccharides, and adhesion proteins. The Vibrio cholerae biofilm matrix contains three major protein components, R...

journal_title：Journal of bacteriology

authors： Giglio KM,Fong JC,Yildiz FH,Sondermann H

更新日期：2013-07-01 00:00:00

abstract：:The Gram-positive Corynebacterium glutamicum efficiently metabolizes maltose by a pathway involving maltodextrin and glucose formation by 4-α-glucanotransferase, glucose phosphorylation by glucose kinases, and maltodextrin degradation via maltodextrin phosphorylase and α-phosphoglucomutase. However, maltose uptake in ...

journal_title：Journal of bacteriology

authors： Henrich A,Kuhlmann N,Eck AW,Krämer R,Seibold GM

更新日期：2013-06-01 00:00:00

abstract：:The intestinal pathogen Clostridium difficile is known to grow only within the intestines of mammals, yet little is known about how the bacterium subsists in this environment. In the intestine, C. difficile must contend with innate defenses within the host, such as cationic antimicrobial peptides (CAMPs) produced by t...

journal_title：Journal of bacteriology

authors： Suárez JM,Edwards AN,McBride SM

更新日期：2013-06-01 00:00:00

abstract：:The enzymes LinB(UT) and LinB(MI) (LinB from Sphingobium japonicum UT26 and Sphingobium sp. MI1205, respectively) catalyze the hydrolytic dechlorination of β-hexachlorocyclohexane (β-HCH) and yield different products, 2,3,4,5,6-pentachlorocyclohexanol (PCHL) and 2,3,5,6-tetrachlorocyclohexane-1,4-diol (TCDL), respecti...

journal_title：Journal of bacteriology

authors： Okai M,Ohtsuka J,Imai LF,Mase T,Moriuchi R,Tsuda M,Nagata K,Nagata Y,Tanokura M

更新日期：2013-06-01 00:00:00

abstract：:In Bacillus thuringiensis, a novel N-acetylmuramoyl-L-alanine amidase gene (named cwlB) was detected, and the CwlB protein was purified and characterized. Reverse transcription-PCR (RT-PCR) results indicated that cwlB and an upstream gene (named cwlA) formed one transcriptional unit. 5' rapid amplification of cDNA end...

journal_title：Journal of bacteriology

authors： Yang J,Peng Q,Chen Z,Deng C,Shu C,Zhang J,Huang D,Song F

更新日期：2013-06-01 00:00:00

abstract：:Clostridium perfringens causes gas gangrene and gastrointestinal (GI) diseases in humans. The most common cause of C. perfringens-associated food poisoning is the consumption of C. perfringens vegetative cells followed by sporulation and production of enterotoxin in the gut. Despite the importance of spore formation i...

journal_title：Journal of bacteriology

authors： Ohtani K,Hirakawa H,Paredes-Sabja D,Tashiro K,Kuhara S,Sarker MR,Shimizu T

更新日期：2013-06-01 00:00:00

abstract：:Three evolutionarily distinct families of replicative DNA polymerases, designated polymerase B (Pol B), Pol C, and Pol D, have been identified. Members of the Pol B family are present in all three domains of life, whereas Pol C exists only in Bacteria and Pol D exists only in Archaea. Pol B enzymes replicate eukaryoti...

journal_title：Journal of bacteriology

authors： Cubonová L,Richardson T,Burkhart BW,Kelman Z,Connolly BA,Reeve JN,Santangelo TJ

更新日期：2013-05-01 00:00:00

abstract：:The activities of DNA methyltransferases are important for a variety of cellular functions in bacteria. In this study, we developed a modified high-throughput technique called methyl homopolymer tail mediated sequencing (methyl HTM-seq) to identify the undermethylated sites in the Vibrio cholerae genome for the two DN...

journal_title：Journal of bacteriology

authors： Dalia AB,Lazinski DW,Camilli A

更新日期：2013-05-01 00:00:00

abstract：:The cold-tolerant bacterium Pusillimonas sp. strain T7-7 is able to utilize diesel oils (C5 to C30 alkanes) as a sole carbon and energy source. In the present study, bioinformatics, proteomics, and real-time reverse transcriptase PCR approaches were used to identify the alkane hydroxylation system present in this bact...

journal_title：Journal of bacteriology

authors： Li P,Wang L,Feng L

更新日期：2013-05-01 00:00:00

abstract：:Many bacteria can accumulate glycine betaine for osmoprotection and catabolize it as a growth substrate, but how they regulate these opposing roles is poorly understood. In Pseudomonas syringae B728a, expression of the betaine catabolism genes was reduced by an osmotic upshift to an intermediate stress level, consiste...

journal_title：Journal of bacteriology

authors： Li S,Yu X,Beattie GA

更新日期：2013-05-01 00:00:00

abstract：:Integrating conjugative elements (ICEs) of the SXT/R391 family are major contributors to the spread of antibiotic resistance genes. These elements also catalyze their own diversity by promoting inter-ICE recombination through the action of the RecA-independent homologous recombination system that they encode. Here, we...

journal_title：Journal of bacteriology

authors： Garriss G,Poulin-Laprade D,Burrus V

更新日期：2013-05-01 00:00:00

abstract：:Toxin-antitoxin (TA) systems have been reported in the genomes of most bacterial species, and their role when located on the chromosome is still debated. TA systems are particularly abundant in the massive cassette arrays associated with chromosomal superintegrons (SI). Here, we describe the characterization of two su...

journal_title：Journal of bacteriology

authors： Guérout AM,Iqbal N,Mine N,Ducos-Galand M,Van Melderen L,Mazel D

更新日期：2013-05-01 00:00:00

abstract：:Pseudomonas aeruginosa type IV pili (T4P) are virulence factors that promote infection of cystic fibrosis and immunosuppressed patients. As the absence of T4P impairs colonization, they are attractive targets for the development of novel therapeutics. Genes in the pilMNOPQ operon are important for both T4P assembly an...

journal_title：Journal of bacteriology

authors： Tammam S,Sampaleanu LM,Koo J,Manoharan K,Daubaras M,Burrows LL,Howell PL

更新日期：2013-05-01 00:00:00

abstract：:Aeromonas hydrophila AH-3 lateral flagella are not assembled when bacteria grow in liquid media; however, lateral flagellar genes are transcribed. Our results indicate that A. hydrophila lateral flagellar genes are transcribed at three levels (class I to III genes) and share some similarities with, but have many impor...

journal_title：Journal of bacteriology

authors： Wilhelms M,Gonzalez V,Tomás JM,Merino S

更新日期：2013-04-01 00:00:00

abstract：:Hydrogenotrophic methanogenic Archaea are defined by an H2 requirement for growth. Despite this requirement, many hydrogenotrophs are also capable of growth with formate as an electron donor for methanogenesis. While certain responses of these organisms to hydrogen availability have been characterized, responses to fo...

journal_title：Journal of bacteriology

authors： Costa KC,Yoon SH,Pan M,Burn JA,Baliga NS,Leigh JA

更新日期：2013-04-01 00:00:00

abstract：:Pseudomonas aeruginosa in the lungs of cystic fibrosis (CF) patients is characterized by a series of genotypic and phenotypic changes that reflect the transition from acute to chronic infection. These include the overproduction of the exopolysaccharide alginate and the loss of complete lipopolysaccharide (LPS). LPS is...

journal_title：Journal of bacteriology

authors： Davis MR Jr,Muszynski A,Lollett IV,Pritchett CL,Carlson RW,Goldberg JB

更新日期：2013-04-01 00:00:00

abstract：:Azotobacter vinelandii is a bacterium which undergoes a differentiation process leading to the formation of metabolically dormant cysts. During the encystment process, A. vinelandii produces alkylresorcinol lipids (ARs) that replace the membrane phospholipids and are also components of the layers covering the cyst. Th...

journal_title：Journal of bacteriology

authors： Romero Y,Moreno S,Guzmán J,Espín G,Segura D

更新日期：2013-04-01 00:00:00

abstract：:Mycoplasma pneumoniae exhibits a novel form of gliding motility that is mediated by the terminal organelle, a differentiated polar structure. Given that genes known to be involved in gliding in other organisms are absent in M. pneumoniae, random transposon mutagenesis was employed to generate mutants with gliding-defi...

journal_title：Journal of bacteriology

authors： Page CA,Krause DC

更新日期：2013-04-01 00:00:00

abstract：:Streptococcus suis serotype 2 is a highly invasive, extracellular pathogen in pigs with the capacity to cause severe infections in humans. This study was initiated by the finding that IgM degradation products are released after opsonization of S. suis. The objective of this work was to identify the bacterial factor re...

journal_title：Journal of bacteriology

authors： Seele J,Singpiel A,Spoerry C,von Pawel-Rammingen U,Valentin-Weigand P,Baums CG

更新日期：2013-03-01 00:00:00

abstract：:Proteus mirabilis, a leading cause of catheter-associated urinary tract infection (CaUTI), differentiates into swarm cells that migrate across catheter surfaces and medium solidified with 1.5% agar. While many genes and nutrient requirements involved in the swarming process have been identified, few studies have addre...

journal_title：Journal of bacteriology

authors： Armbruster CE,Hodges SA,Mobley HL

更新日期：2013-03-01 00:00:00

abstract：:Movement over an agar surface via swarming motility is subject to formidable challenges not encountered during swimming. Bacteria display a great deal of flexibility in coping with these challenges, which include attracting water to the surface, overcoming frictional forces, and reducing surface tension. Bacteria that...

journal_title：Journal of bacteriology

authors： Partridge JD,Harshey RM

更新日期：2013-03-01 00:00:00

abstract：:Lipopolysaccharide is a major glycolipid component in the outer leaflet of the outer membrane (OM), a peculiar permeability barrier of Gram-negative bacteria that prevents many toxic compounds from entering the cell. Lipopolysaccharide transport (Lpt) across the periplasmic space and its assembly at the Escherichia co...

journal_title：Journal of bacteriology

authors： Villa R,Martorana AM,Okuda S,Gourlay LJ,Nardini M,Sperandeo P,Dehò G,Bolognesi M,Kahne D,Polissi A

更新日期：2013-03-01 00:00:00

abstract：:Necrotic enteritis (NE) is an economically important disease of poultry caused by certain Clostridium perfringens type A strains. NE pathogenesis involves the NetB toxin, which is encoded on a large conjugative plasmid within a 42-kb pathogenicity locus. Recent multilocus sequence type (MLST) studies have identified t...

journal_title：Journal of bacteriology

authors： Lepp D,Gong J,Songer JG,Boerlin P,Parreira VR,Prescott JF

更新日期：2013-03-01 00:00:00

abstract：:Silicibacter sp. strain TM1040, a member of the Roseobacter clade, forms a symbiosis with unicellular phytoplankton, which is inextricably linked to the biphasic "swim or stick" lifestyle of the bacteria. Mutations in flaC bias the population toward the motile phase. Renewed examination of the FlaC(-) strain (HG1016) ...

journal_title：Journal of bacteriology

authors： Sule P,Belas R

更新日期：2013-02-01 00:00:00

abstract：:Escherichia coli contains 30 two-component systems (TCSs), each consisting of a histidine kinase and a response regulator. Whereas most TCSs are well characterized in this model organism, little is known about the YpdA/YpdB system. To identify YpdB-regulated genes, we compared the transcriptomes of E. coli cells overp...

journal_title：Journal of bacteriology

authors： Fried L,Behr S,Jung K

更新日期：2013-02-01 00:00:00